Prevention of meningococcal disease

被引:64
作者
Gardner, Pierce [1 ]
机构
[1] SUNY Stony Brook, Sch Med, Dept Med, Stony Brook, NY 11794 USA
[2] SUNY Stony Brook, Sch Med, Grad Program Publ Hlth, Stony Brook, NY 11794 USA
关键词
D O I
10.1056/NEJMcp063561
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A previously healthy 18-year-old college freshman presented to an emergency department with acute onset of fever and headache. He was listless and in distress. His temperature was 40.0 degrees C, his pulse was 140 per minute, his blood pressure was 70/40 mm Hg, and his respirations were 35 per minute. Petechiae were noted over his thorax. Meningococcal septicemia was suspected ( and subsequently confirmed by the growth of Neisseria meningitidis serogroup C isolated from blood). Despite the prompt administration of antibiotics and other support, the patient's illness was fulminant and he died 12 hours after the onset of the symptoms. Should he have previously received meningococcal vaccine, and what measures should be taken to protect his close contacts and his community?
引用
收藏
页码:1466 / 1473
页数:8
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