A privileged role for neuronal Na+ channels in regulating ventricular [Ca2+] and arrhythmias

被引:0
|
作者
Jones, DeAnalisa C. [1 ]
Gong, Jingqi Q. X. [1 ]
Sobie, Eric A. [1 ]
机构
[1] Icahn Sch Med Mt Sinai, Grad Sch Biomed Sci, Dept Pharmacol Sci, New York, NY 10029 USA
来源
JOURNAL OF GENERAL PHYSIOLOGY | 2018年 / 150卷 / 07期
基金
美国国家卫生研究院; 美国国家科学基金会;
关键词
LONG QT SYNDROME; BETA-ADRENERGIC STIMULATION; SARCOPLASMIC-RETICULUM; NA+-CA2+ EXCHANGE; CARDIAC MYOCYTES; EARLY AFTERDEPOLARIZATIONS; ALLOSTERIC ACTIVATION; PROTEIN-KINASE; RELEASE; CAMKII;
D O I
10.1085/jgp.201812120
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
引用
收藏
页码:901 / 905
页数:5
相关论文
共 50 条
  • [31] Effects of a Lasiodora spider venom on Ca2+ and Na+ channels
    Kushmerick, C
    de Carvalho, FM
    de Maria, M
    Massensini, AR
    Romano-Silva, MA
    Gomez, MV
    Kalapothakis, E
    Prado, MAM
    TOXICON, 2001, 39 (07) : 991 - 1002
  • [32] Forefront of Na+/Ca2+ exchanger studies:: Role of Na+/Ca2+ exchanger -: Lessons from knockout mice
    Komuro, I
    Ohtsuka, M
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 2004, 96 (01) : 23 - 26
  • [33] Role of Na+/Ca2+ exchange in regulating cytosolic Ca2+ in cultured human pulmonary artery smooth muscle cells
    Zhang, S
    Yuan, JXJ
    Barrett, KE
    Dong, H
    AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2005, 288 (02): : C245 - C252
  • [35] Na+ channels and Ca2+ channels of the cell membrane as targets of neuroprotective substances
    Alzheimer, C
    MOLECULAR AND CELLULAR BIOLOGY OF NEUROPROTECTION IN THE CNS, 2002, 513 : 161 - 181
  • [36] Doxorubicin Stimulates the Na+/Ca2+ Exchanger in Ventricular Cardiomyocytes
    Bassani, Rosana A.
    Corrado, Alexandre P.
    Bassani, Jose W.
    BIOPHYSICAL JOURNAL, 2014, 106 (02) : 531A - 531A
  • [37] The Ca2+ pumps and the Na+/Ca2+ exchangers
    Guerini, D
    BIOMETALS, 1998, 11 (04) : 319 - 330
  • [38] Ca2+ regulation of the Na+/Ca2+ exchanger
    Chaptal, Vincent
    Mercado-Besserer, Gabriel
    Ottolia, Michela
    Nicoll, Deborah
    Philipson, Kenneth
    Abramson, Jeff
    FASEB JOURNAL, 2009, 23
  • [39] Selective Na+/Ca2+ exchanger inhibition prevents Ca2+ overload-induced triggered arrhythmias
    Nagy, Norbert
    Kormos, Anita
    Kohajda, Zsofia
    Szebeni, Aron
    Szepesi, Judit
    Pollesello, Piero
    Levijoki, Jouko
    Acsai, Karoly
    Virag, Laszlo
    Nanasi, Peter P.
    Papp, Julius Gy
    Varro, Andras
    Toth, Andras
    BRITISH JOURNAL OF PHARMACOLOGY, 2014, 171 (24) : 5665 - 5681
  • [40] Inactivation kinetics of Na+, Ca2+, and Ba2+ current through cardiac Na+ channels
    Sobie, EA
    Guatimosim, S
    Cruz, J
    Lederer, WJ
    BIOPHYSICAL JOURNAL, 2000, 78 (01) : 85A - 85A