Diastereoselective amination of vinylic sulfoximines:: application to the asymmetric synthesis of functionalized β-substituted and β,β-disubstituted β-amino acids, and of γ-amino alcohols

被引：14
|
作者：
Gais, HJ [1 ]
Loo, R [1 ]
Das, P [1 ]
Raabe, G [1 ]
机构：
[1] Rhein Westfal TH Aachen, Inst Organ Chem, D-52056 Aachen, Germany
来源：
TETRAHEDRON LETTERS | 2000年 / 41卷 / 16期
关键词：
D O I：
10.1016/S0040-4039(00)00307-5
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An asymmetric synthesis of protected beta-substituted and beta,beta-disubstituted beta-amino acids, which carry a hydroxyalkyl side chain, from sulfonimidoyl functionalized homoallylic alcohols is described. The method allows for an asymmetric synthesis of amino alcohols as well. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：2851 / 2854
页数：4
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