Stability analysis of the POD reduced order method for solving the bidomain model in cardiac electrophysiology

被引:12
作者
Corrado, Cesare [1 ]
Lassoued, Jamila [2 ]
Mahjoub, Moncef [2 ]
Zemzemi, Nejib [1 ]
机构
[1] INRIA, Bordeaux Sud Ouest, 200 Ave Vielle Tour, F-33405 Talence, France
[2] Univ Tunis El Manar, LAMSIN ENIT, BP 37, Tunis 1002, Tunisia
关键词
Bidomain equation; Reduced order method; Proper orthogonal decomposition; Stability analysis; A priori estimates; Mitchell-Schaeffer model; PROPER ORTHOGONAL DECOMPOSITION; PROPAGATION; EQUATIONS; TISSUE;
D O I
10.1016/j.mbs.2015.12.005
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
In this paper we show the numerical stability of the Proper Orthogonal Decomposition (POD) reduced order method used in cardiac electrophysiology applications. The difficulty of proving the stability comes from the fact that we are interested in the bidomain model, which is a system of degenerate parabolic equations coupled to a system of ODEs representing the cell membrane electrical activity. The proof of the stability of this method is based on a priori estimates controlling the gap between the reduced order solution and the Galerkin finite element one. We present some numerical simulations confirming the theoretical results. We also combine the POD method with a time splitting scheme allowing a faster solving of the bidomain problem and show numerical results. Finally, we conduct numerical simulation in 2D illustrating the stability of the POD method in its sensitivity to the ionic model parameters. We also perform 3D simulation using a massively parallel code. We show the computational gain using the POD reduced order model. We also show that this method has a better scalability than the full finite element method. (C) 2015 Elsevier Inc. All rights reserved.
引用
收藏
页码:81 / 91
页数:11
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