Two-Photon Fluorescent Probes for Metal Ions in Live Tissues

被引：72
作者：
Sarkar, Avik Ranjan [1 ]
Kang, Dong Eun [2 ]
Kim, Hwan Myung [1 ]
Cho, Bong Rae [2 ]
机构：
[1] Ajou Univ, Div Energy Syst Res, Suwon 443749, South Korea
[2] Korea Univ, Dept Chem, Seoul 136701, South Korea
来源：
INORGANIC CHEMISTRY | 2014年 / 53卷 / 04期
基金：
新加坡国家研究基金会;
关键词：
MEMBRANE CALCIUM-IONS; CELL-DEATH; ZINC IONS; CHEMISTRY; SENSORS; OXYGEN; ZN2+; CA2+; MICROSCOPY; BIOLOGY;
D O I：
10.1021/ic402475f
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Two-photon microscopy (TPM) is a new imaging tool that can detect biological targets deep inside a live tissue. To faciltate the use of TPM in biomedical research, a variety of two-photon (TP) probes for specific applications are needed. In this Forum Article, we describe the design strategy, photophysical properties, and biological imaging applications of a selection of our recent studies in the development of TP probes for metal ions. Small-molecule TP turn-on probes, organelle-targeted probes, and multicolor emissive probes for dual-color imaging are briefly reviewed.
引用
收藏
页码：1794 / 1803
页数：10
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