Preparation of novel pyrrol-2-one derivatives via an effective synthesis of new oxazole scaffold

被引：12

作者：

Kibriz, Ibrahim Evren ^{[1
]}

Sacmaci, Mustafa ^{[1
]}

Sahin, Ertan ^{[2
]}

Yildirim, Ismail ^{[3
]}

机构：

[1] Bozok Univ, Fac Arts & Sci, Dept Chem, TR-66200 Yozgat, Turkey

[2] Ataturk Univ, Fac Sci, Dept Chem, TR-25240 Erzurum, Turkey

[3] Erciyes Univ, Fac Sci, Dept Chem, TR-38039 Kayseri, Turkey

来源：

TETRAHEDRON | 2017年 / 73卷 / 14期

关键词：

Furan-2,3-dione; Cyanamide; Oxazole; Pyrrole; Cycloaddition; CYCLIC OXALYL COMPOUNDS; SUBSTITUTED PYRROLES; EFFICIENT SYNTHESIS; CYCLIZATION; THIAZOLE; ANALOGS;

D O I：

10.1016/j.tet.2017.01.046

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A convenient procedure for the preparation of oxazole and pyrrole derivatives is described. 2-Amino-1,3-oxazol-2-ones 3a,b were first synthesized from the cyclocondensation reactions of cyanamide (2) with 4-ethoxycarbonyl-5-aryl-2,3-furandione 1a,b, and then new pyrrol-2-ones 5 were synthesized from the reaction of the compounds 3 with various aromatic amines 4. (C) 2017 Published by Elsevier Ltd.

引用

页码：1795 / 1802

页数：8

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