The human basonuclin gene

被引：17

作者：

Teumer, J ^{[1
]}

Tseng, H ^{[1
]}

Green, H ^{[1
]}

机构：

[1] HARVARD UNIV,SCH MED,DEPT CELL BIOL,BOSTON,MA 02115

来源：

GENE | 1997年 / 188卷 / 01期

关键词：

zinc fingers; CpG dinucleotides; G+C-rich promoters;

D O I：

10.1016/S0378-1119(96)00659-2

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The human gene for basonuclin, a zinc-finger protein of keratinocytes, has been cloned, sequenced and assigned to chromosome 15. The transcription unit spans nearly 29 kb of sequence. The coding region is distributed over five exons, and the three pairs of zinc fingers are encoded by the last two. The 5' flanking sequence and first exon are unusually rich in G+C and in CpG dinucleotides. This region contains numerous target sites for the transcription factor Spl.

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页码：1 / 7

页数：7

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