Designed Strategies for Fluorescence-Based Biosensors for the Detection of Mycotoxins

被引:66
作者
Sharma, Atul [1 ,2 ,5 ]
Khan, Reem [1 ,3 ,4 ]
Catanante, Gaelle [1 ]
Sherazi, Tauqir A. [3 ]
Bhand, Sunil [2 ]
Hayat, Akhtar [4 ]
Marty, Jean Louis [1 ]
机构
[1] Univ Perpignan, BAE, Via Domitia,52 Ave Paul Alduy, F-66860 Perpignan, France
[2] Birla Inst Technol & Sci, Dept Chem, Biosensor Lab, Pilani KK Birla Goa Campus, Zuarinagar 403726, Goa, India
[3] COMSATS Inst Informat Technol, Dept Chem, Abbottabad 22060, Pakistan
[4] COMSATS Inst Informat Technol, IRCBM, Lahore 54000, Pakistan
[5] MVN Univ, Sch Pharmaceut Sci, Palwal 121105, Haryana, India
来源
TOXINS | 2018年 / 10卷 / 05期
关键词
mycotoxins; fluorescence assay; biosensors; nanomaterials; fluorescence quenching; food samples; STRUCTURE-SWITCHING APTAMER; ENERGY-TRANSFER APTASENSOR; LATERAL FLOW IMMUNOASSAY; SENSITIVE DETECTION; QUANTUM DOTS; LABEL-FREE; SILICA NANOPARTICLES; POLARIZATION IMMUNOASSAY; GRAPHENE OXIDE; AFLATOXIN M-1;
D O I
10.3390/toxins10050197
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Small molecule toxins such as mycotoxins with low molecular weight are the most widely studied biological toxins. These biological toxins are responsible for food poisoning and have the potential to be used as biological warfare agents at the toxic dose. Due to the poisonous nature of mycotoxins, effective analysis techniques for quantifying their toxicity are indispensable. In this context, biosensors have been emerged as a powerful tool to monitors toxins at extremely low level. Recently, biosensors based on fluorescence detection have attained special interest with the incorporation of nanomaterials. This review paper will focus on the development of fluorescence-based biosensors for mycotoxin detection, with particular emphasis on their design as well as properties such as sensitivity and specificity. A number of these fluorescent biosensors have shown promising results in food samples for the detection of mycotoxins, suggesting their future potential for food applications.
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页数:19
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