Synthesis of 2,4,5-triarylated imidazoles via three-component domino reaction under catalyst-free conditions

被引：14

作者：

Chen, Yang ^{[2
]}

Wang, Ren ^{[3
]}

Ba, Feifei ^{[2
]}

Hou, Junli ^{[2
]}

Ding, Aishun ^{[1
]}

Zhou, Mingdong ^{[2
]}

Guo, Hao ^{[1
]}

机构：

[1] Fudan Univ, Dept Chem, 220 Handan Rd, Shanghai 200433, Peoples R China

[2] Liaoning Shihua Univ, Sch Chem & Mat Sci, Dandong Rd 1, Fushun 113001, Peoples R China

[3] Shanghai Jiao Tong Univ, Affiliated Peoples Hosp 6, Shanghai Inst Ultrasound Med, Dept Ultrasound Med, Shanghai 200233, Peoples R China

来源：

JOURNAL OF SAUDI CHEMICAL SOCIETY | 2017年 / 21卷 / 01期

基金：

对外科技合作项目（国际科技项目）;

关键词：

Three-component domino reaction; Imidazole; Catalyst-free; Synthesis; Green chemistry; ONE-POT SYNTHESIS; 2,4,5-TRISUBSTITUTED IMIDAZOLES; MICROWAVE IRRADIATION; EFFICIENT; 2,4,5-TRIARYLIMIDAZOLES; DERIVATIVES; INHIBITORS;

D O I：

10.1016/j.jscs.2016.03.001

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A one-pot synthesis of 2,4,5-triarylated imidazoles via three-component domino reaction of 2,2-dibromo-1,2-diarylethanones, ammonium acetate, and aryl aldehydes under catalyst-free conditions is developed. The scope of this reaction is studied. A possible mechanism is proposed based on experimental results. (C) 2016 King Saud University. Production and hosting by Elsevier B.V.

引用

页码：76 / 81

页数：6

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