At the crossroads of growth control; making ribosomal RNA

被引：128
作者：
Moss, T
机构：
[1] Univ Laval, Hotel Dieu Quebec, Canc Res Ctr, Quebec City, PQ G1R 2J6, Canada
[2] Univ Laval, Hotel Dieu Quebec, Dept Med Biol, Quebec City, PQ G1R 2J6, Canada
来源：
CURRENT OPINION IN GENETICS & DEVELOPMENT | 2004年 / 14卷 / 02期
基金：
加拿大健康研究院;
关键词：
D O I：
10.1016/j.gde.2004.02.005
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Although the mechanisms of cell cycle control are well established, the factors controlling cell growth and target size are still poorly understood. Much evidence suggests that ribosome biogenesis, and in particular the synthesis of the rRNAs, plays a central role not only in permitting growth, but also in regulating it. In the past few years we have begun to penetrate the network linking rRNA gene transcription to growth.
引用
收藏
页码：210 / 217
页数：8
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