Metaplastic breast carcinoma: more than a special type

被引：71

作者：

Weigelt, Britta ^{[1
]}

Eberle, Carey ^{[1
]}

Cowell, Catherine F. ^{[1
]}

Ng, Charlotte K. Y. ^{[1
]}

Reis-Filho, Jorge S. ^{[1
]}

机构：

[1] Mem Sloan Kettering Canc Ctr, Dept Pathol, New York, NY 10065 USA

来源：

NATURE REVIEWS CANCER | 2014年 / 14卷 / 03期

关键词：

CANCER; TUMORS; PATHWAY; GENES; BRCA1; P53;

D O I：

10.1038/nrc3637

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Metaplastic breast carcinoma (MBC) is a special histological type of invasive breast cancer. MBC is a descriptive and operational term for a heterogeneous collection of tumours with distinct histologies, clinical behaviours and potentially responses to therapy. © 2014 Macmillan Publishers Limited.

引用

页码：147 / 148

页数：2

共 13 条

[1] Molecular analysis reveals a genetic basis for the phenotypic diversity of metaplastic breast carcinomas [J].

Geyer, Felipe C. ;

Weigelt, Britta ;

Natrajan, Rachael ;

Lambros, Maryou B. K. ;

de Blase, Dario ;

Vatcheva, Radost ;

Savage, Kay ;

Mackay, Alan ;

Ashworth, Alan ;

Reis-Filho, Jorge S. .

JOURNAL OF PATHOLOGY, 2010, 220 (05) :562-573

[2] Genetic changes of Wnt pathway genes are common events in metaplastic carcinomas of the breast [J].

Hayes, Michael J. ;

Thomas, Dafydd ;

Emmons, Agnieszka ;

Giordano, Thomas J. ;

Kleer, Celina G. .

CLINICAL CANCER RESEARCH, 2008, 14 (13) :4038-4044

[3] Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics [J].

Hennessy, Bryan T. ;

Gonzalez-Angulo, Ana-Maria ;

Stemke-Hale, Katherine ;

Gilcrease, Michael Z. ;

Krishnamurthy, Savitri ;

Lee, Ju-Seog ;

Fridlyand, Jane ;

Sahin, Aysegul ;

Agarwal, Roshan ;

Joy, Corwin ;

Liu, Wenbin ;

Stivers, David ;

Baggerly, Keith ;

Carey, Mark ;

Lluch, Ana ;

Monteagudo, Carlos ;

He, Xiaping ;

Weigman, Victor ;

Fan, Cheng ;

Palazzo, Juan ;

Hortobagyi, Gabriel N. ;

Nolden, Laura K. ;

Wang, Nicholas J. ;

Valero, Vicente ;

Gray, Joe W. ;

Perou, Charles M. ;

Mills, Gordon B. .

CANCER RESEARCH, 2009, 69 (10) :4116-4124

[4]

Ince TA, 2007, CANCER CELL, V12, P160, DOI 10.1016/j.ccr.2007.06.013

[5] β-catenin/Wnt signalling pathway in fibromatosis, metaplastic carcinomas and phyllodes tumours of the breast [J].

Lacroix-Triki, Magali ;

Geyer, Felipe C. ;

Lambros, Maryou B. ;

Savage, Kay ;

Ellis, Ian O. ;

Lee, Andrew H. S. ;

Reis-Filho, Jorge S. .

MODERN PATHOLOGY, 2010, 23 (11) :1438-1448

[6]

Lakhani S.R., WHO Classification of Tumours of the Breast, VFourth

[7] P53 overexpression and mutation in metaplastic carcinoma of the breast: genetic evidence for a monoclonal origin of both the carcinomatous and the heterogeneous sarcomatous components [J].

Lien, HC ;

Lin, CW ;

Mao, TL ;

Kuo, SH ;

Hsiao, CH ;

Huang, CS .

JOURNAL OF PATHOLOGY, 2004, 204 (02) :131-139

[8]

Liu X., P NATL ACAD SCI US, V104, P12111

[9] BRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells [J].

Molyneux, Gemma ;

Geyer, Felipe C. ;

Magnay, Fiona-Ann ;

McCarthy, Afshan ;

Kendrick, Howard ;

Natrajan, Rachael ;

MacKay, Alan ;

Grigoriadis, Anita ;

Tutt, Andrew ;

Ashworth, Alan ;

Reis-Filho, Jorge S. ;

Smalley, Matthew J. .

CELL STEM CELL, 2010, 7 (03) :403-417

[10] EGFR amplification and lack of activating mutations in metaplastic breast carcinomas [J].

Reis, J. S. ;

Pinheiro, C. ;

Lambros, M. B. K. ;

Milanezi, F. ;

Carvalho, S. ;

Savage, K. ;

Simpson, P. T. ;

Jones, C. ;

Swift, S. ;

Mackay, A. ;

Reis, R. M. ;

Hornick, J. L. ;

Pereira, E. M. ;

Baltazar, F. ;

Fletcher, C. D. M. ;

Ashworth, A. ;

Lakhani, S. R. ;

Schmitt, F. C. .

JOURNAL OF PATHOLOGY, 2006, 209 (04) :445-453

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