Obstetric outcomes in pregnancy with pulmonary hypertension: A retrospective study of 78 cases at one center

ObjectiveTo identify the vary of obstetric outcomes by the severity of pulmonary hypertension (PH). MethodsA retrospective study involved pregnancies with PH in one certain academic institution. Total 78 pregnancies with PH were classified into three groups according the mean pulmonary arterial systolic pressure: mean pulmonary arterial systolic pressure 30-49 mm Hg (mild-PH group), mean pulmonary arterial systolic pressure 50-69 mm Hg (moderate-PH group) and mean pulmonary arterial systolic pressure 70 mm Hg (severe-PH group). The clinical features and obstetric outcomes were described and compared among three groups. ResultsThe incidence of PH was 0.23%, including 57 cases in mild-PH group, 10 cases in moderate-PH group and 11 cases in severe-PH group. Meanwhile, pregnancies with mild PH present NYHA class I/II (P < 0.001). General anesthesia (P < 0.001) and advanced intensive care (P = 0.011) were supplied for pregnancies with severe PH. There was no significant difference in rate of caesarean delivery. Furthermore, severity of PH increased the risk of neonatal death (P = 0.040). ConclusionThe severity of PH seems to be a poor prognosis of neonatal death. Intensive care should be provided for pregnancies with severe PH.