A Facile Synthesis of Furo[3,4-e]pyrazolo[3,4-b]pyridine-5(7H)-one Derivatives via Three-Component Reaction in Ionic Liquid without Any Catalyst

被引：33
|
作者：
Shi, Da-Qing [1 ,2 ]
Yang, Fang [2 ]
Ni, Sai-Nan [2 ]
机构：
[1] Soochow Univ, Key Lab Organ Synth Jiangsu Prov, Coll Chem Chem Engn & Mat Sci, Suzhou 215123, Peoples R China
[2] Xuzhou Normal Univ, Coll Chem & Chem Engn, Xuzhou 221116, Peoples R China
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 2009年 / 46卷 / 03期
关键词：
ONE-POT SYNTHESIS; TRICYCLIC ANALOGS; CHEMISTRY; HYDROGENATION; ALKYLATION; CONVERSION; SOLVENTS; NK-1; ACID;
D O I：
10.1002/jhet.103
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A series of furo[3,4-e]pyrazolo[3,4-b]pyridine-5(7H)-one and indeno[2,1-e]pyridinzolo[3,4-b]pyridine5(7H)-one derivatives were synthesized via the three-conponent reaction of an aldehyde, 5-aminopyrazole and either tetronic acid or 1,3-indanedione in ionic liquid without any catalyst. The structures of the products have been established by spectroscopic data and further confirmed by X-ray diffraction, analysis. This method has the advantages of easier work-up, mild reaction conditions, high yields and an environmentally benign procedure.
引用
收藏
页码：469 / 476
页数：8
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