Results of Construction of Protective Loop Ileostomies and Reversal Surgery for Colorectal Surgery

被引:8
作者
Abegg, R. M. [1 ,2 ]
Brokelman, W. [1 ,2 ]
van Bebber, I. P. [1 ,2 ]
Bosscha, K. [1 ,2 ]
Prins, H. A. [1 ,2 ]
Lips, D. J. [1 ,2 ]
机构
[1] Jeroen Bosch Hosp, Dept Surg Oncol, NL-5200 ME sHertogenbosch, Netherlands
[2] Jeroen Bosch Hosp, Dept Gastrointestinal Surg, NL-5200 ME sHertogenbosch, Netherlands
关键词
Ileostomy complications; Ileostomy closure; Ileostomy reversal; Loop ileostomy; LOW ANTERIOR RESECTION; TOTAL MESORECTAL EXCISION; ANASTOMOTIC LEAKAGE; DEFUNCTIONING STOMA; LAPAROSCOPIC MANAGEMENT; CURATIVE RESECTION; CANCER; MULTICENTER; SURVIVAL; COMPLICATIONS;
D O I
10.1159/000357053
中图分类号
R61 [外科手术学];
学科分类号
摘要
Background: Protective loop ileostomies in colorectal surgery are constructed to reduce morbidity and reinterventions related to the primary operation. However, ileostomies are associated with stoma-related morbidity and postoperative complications following reversal surgery. Dutch national data show increased use of loop ileostomies in colorectal surgery for cancer justifying an adequate assessment of its morbidity. This study was undertaken to investigate morbidity associated with protective loop ileostomies in colorectal surgery. Methods: Retrospectively, 118 consecutive patients undergoing left-sided colonic or rectal resection with protective loop ileostomy were included. Primary outcome was 30-day mortality. Secondary endpoints included total complication rate (including stoma-related morbidity), total reintervention risk, anastomotic leakage risk and total length of stay. Results: No mortality was observed. Overall major complication, reintervention and anastomotic leakage risk for colorectal surgery were 20, 20 and 3.9%, respectively. Combined length of stay for stoma-related morbidity and reversal surgery was 12.7 days. The risk for stoma-related morbidity was 35%, and the risk for nonelective reversal was 12%. Closure rate (mean follow-up of 15 months) was 87% with a mean interval of 125 days. Reversal surgery was not correlated with mortality but with major complications (11%) and reintervention risk, anastomotic leakage risk (3.8%) and a mean length of stay of 9 days. Conclusion: Construction of loop ileostomies in left-sided colonic or rectal resection is associated with a low risk for anastomotic leakage at the expense of substantial stoma-related morbidity and morbidity related to reversal surgery. More accurate identification of colorectal cancer patients benefitting from protective loop ileostomy seems to be warranted. (C) 2014 S. Karger AG, Basel
引用
收藏
页码:63 / 72
页数:10
相关论文
共 24 条
[1]   A NEW METHOD OF CLASSIFYING PROGNOSTIC CO-MORBIDITY IN LONGITUDINAL-STUDIES - DEVELOPMENT AND VALIDATION [J].
CHARLSON, ME ;
POMPEI, P ;
ALES, KL ;
MACKENZIE, CR .
JOURNAL OF CHRONIC DISEASES, 1987, 40 (05) :373-383
[2]   The morbidity surrounding reversal of defunctioning ileostomies: a systematic review of 48 studies including 6,107 cases [J].
Chow, Andre ;
Tilney, Henry S. ;
Paraskeva, Paraskevas ;
Jeyarajah, Santhini ;
Zacharakis, Emmanouil ;
Purkayastha, Sanjay .
INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 2009, 24 (06) :711-723
[3]   The Clavien-Dindo Classification of Surgical Complications Five-Year Experience [J].
Clavien, Pierre A. ;
Barkun, Jeffrey ;
de Oliveira, Michelle L. ;
Vauthey, Jean Nicolas ;
Dindo, Daniel ;
Schulick, Richard D. ;
de Santibanes, Eduardo ;
Pekolj, Juan ;
Slankamenac, Ksenija ;
Bassi, Claudio ;
Graf, Rolf ;
Vonlanthen, Rene ;
Padbury, Robert ;
Cameron, John L. ;
Makuuchi, Masatoshi .
ANNALS OF SURGERY, 2009, 250 (02) :187-196
[4]   Multicentre analysis of oncological and survival outcomes following anastomotic leakage after rectal cancer surgery [J].
den Dulk, M. ;
Marijnen, C. A. M. ;
Collette, L. ;
Putter, H. ;
Pahlman, L. ;
Folkesson, J. ;
Bosset, J. -F. ;
Roedel, C. ;
Bujko, K. ;
van de Velde, C. J. H. .
BRITISH JOURNAL OF SURGERY, 2009, 96 (09) :1066-1075
[5]   A multivariate analysis of limiting factors for stoma reversal in patients with rectal cancer entered into the total mesorectal excision (TME) trial: a retrospective study [J].
den Dulk, Marcel ;
Smit, Marije ;
Peeters, Koen C. M. J. ;
Kranenbarg, Elma Meershoek-Klein ;
Rutten, Harm J. T. ;
Wiggers, Theo ;
Putter, Hein ;
van de Velde, Cornelis J. H. .
LANCET ONCOLOGY, 2007, 8 (04) :297-303
[6]  
DICA, 2011, DUTCH I CLIN AUD ANN
[7]  
DSCA, 2009, DUTCH SURG COL AUD A
[8]  
DSCA, 2010, DUTCH SURG COL AUD A
[9]   Protective defunctioning stoma in low anterior resection for rectal carcinoma [J].
Gastinger, I ;
Marusch, F ;
Steinert, R ;
Wolff, S ;
Koeckerling, F ;
Lippert, H .
BRITISH JOURNAL OF SURGERY, 2005, 92 (09) :1137-1142
[10]   Short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer (MRC CLASICC trial): multicentre, randomised controlled trial [J].
Guillou, PJ ;
Quirke, P ;
Thorpe, H ;
Walker, J ;
Jayne, DG ;
Smith, AMH ;
Heath, RM ;
Brown, JM .
LANCET, 2005, 365 (9472) :1718-1726