This paper studies the influence of different substrate materials on the phase composition, microstructure, microhardness, and wear resistance of Ni-Cr-B-Si-C-Ti-Al plasma spray coatings. Two types of substrate metals were studied - AISI 1045 steel and Pig-P3 Si grey cast iron. It has been found that in the as-coated condition the surface layers have a phase composition of 7-Ni, Cr23C6, 7-TiAl, TiN, and alpha-Ti(N, O) on steel substrate, and 7-Ni, alpha-Ti, TiN, Ni3B, CrB, Cr23C6, alpha-Ti(N, O), Ni3Si on cast iron. The microhardness and wear resistance of the plasma sprayed Ni-Cr-B-Si-C-Ti-Al coatings is tested. The wear volume of the coatings has been tested for up to 60 min. The de-posits on cast iron substrates demonstrate lower wear than those on the steel substrate.