Race and Ethnicity in Cancer Therapy: What Have We Learned?

被引：25

作者：

Grenade, C. ^{[1
,2
]}

Phelps, M. A. ^{[1
,3
]}

Villalona-Calero, M. A. ^{[1
,2
]}

机构：

[1] Ohio State Univ, Dept Internal Med, Div Med Oncol, Columbus, OH 43210 USA

[2] Ohio State Univ, Ctr Comprehens Canc, Columbus, OH 43210 USA

[3] Ohio State Univ, Coll Pharm, Div Pharmaceut, Columbus, OH 43210 USA

来源：

CLINICAL PHARMACOLOGY & THERAPEUTICS | 2014年 / 95卷 / 04期

关键词：

CELL LUNG-CANCER; BREAST-CANCER; AFRICAN-AMERICAN; RACIAL-DIFFERENCES; GENETIC POLYMORPHISMS; CYTOCHROME-P450; 3A4; COLORECTAL-CANCER; WHITE WOMEN; PHASE-II; SURVIVAL;

D O I：

10.1038/clpt.2014.5

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Racial and ethnic disparities in the pathogenesis of common malignancies and outcomes from treatment remain a major health concern. Factors attributed to these disparities include differences in lifestyle, environment, genetics, and tumor biology. As we strive to personalize cancer therapy, it will be imperative that we understand the relative contributions of each factor so that we may apply this knowledge in choosing the best treatment for each individual, regardless of his or her racial or ethnic heritage.

引用

页码：403 / 412

页数：10

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