Comparison of Central Corneal Thickness, Thinnest Corneal Thickness, Anterior Chamber Depth, and Simulated Keratometry Using Galilei, Pentacam, and Sirius Devices

Purpose: The aim was to evaluate the agreement in the central corneal thickness (CCT), thinnest corneal thickness (TCT), anterior chamber depth (ACD), and mean simulated keratometry (simK) measurements using Pentacam, Galilei, and Sirius Scheimpflug systems in normal eyes. Methods: Anterior segment measurements were performed with Pentacam, Galilei, and Sirius devices in 32 healthy subjects. The right eye of each participant was selected. Measurements obtained with the 3 systems were compared using repeated-measures analysis of variance and Bonferroni multiple comparisons test. Results: Analysis of variance determined a significant difference in the anterior segment measurements of CCT, TCT, ACD, and simK between the 3 devices (P < 0.001). Pairwise comparisons of CCT and TCT measurements were significantly different except for the comparison between Pentacam and Sirius. All pairwise comparisons for ACD were statistically significant. The pairwise comparison results for simK values showed that the Galilei and Sirius systems demonstrated better agreement with each other than with Pentacam. Conclusions: The results of this study suggest that the Pentacam, Galilei, and Sirius Scheimpflug systems should not be accepted as interchangeable for CCT, TCT, ACD, and simK in healthy subjects.