Copper-Catalyzed N-Allenylation of Allylic Sulfonamides

被引：33

作者：

Persson, Andreas K. A. ^{[1
]}

Johnston, Eric V. ^{[1
]}

Backvall, Jan-E. ^{[1
]}

机构：

[1] Stockholm Univ, Dept Organ Chem, Arrhenius Lab, SE-10691 Stockholm, Sweden

来源：

ORGANIC LETTERS | 2009年 / 11卷 / 17期

基金：

瑞典研究理事会;

关键词：

BOND FORMATION; ARYL HALIDES; OXIDATIVE CARBOCYCLIZATION; COUPLING REACTIONS; CHIRAL YNAMIDES; CROSS-COUPLINGS; ALLENAMIDES; AMIDES; FACILE; ACIDITIES;

D O I：

10.1021/ol901294j

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Allylic allenic amides have been synthesized via a copper-catalyzed cross-coupling between allylic sulfonamides and bromoallenes in moderate to good yields. Copper(I) thiophene-2-carboxylate (CuTC) was used a source of copper with DMEDA as the ligand. The allenylated products obtained are potential substrates for palladium-catalyzed carbocyclizations.

引用

页码：3814 / 3817

页数：4

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