TiO2 Nanoparticles Catalyzed Chemoselective Synthesis of 2-Chloroquinolinyl-4-quinolinones and their Intramolecular Cyclization through Palladium Catalyzed Sonogashira Coupling Reaction

被引：3
|
作者：
Kumar, Y. Suneel [1 ]
Khan, F. Nawaz [1 ]
机构：
[1] VIT Univ, Vellore, Tamil Nadu, India
来源：
CATALYSIS LETTERS | 2017年 / 147卷 / 04期
关键词：
Chemoselective synthesis; Intramolecular cyclization; Sonogashira coupling reaction; SOLVENT-FREE CONDITIONS; CORRESPONDING 2-ARYL-2,3-DIHYDROQUINOLIN-4(1H)-ONES; EFFICIENT; 2'-AMINOCHALCONES; DERIVATIVES;
D O I：
10.1007/s10562-017-1992-x
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
The 2-chloro-3-formyl quinolines 1, were chemoselectivity and effectively converted into their corresponding 2-chloroquinolinyl-4-quinolinones 3 through Knoevenagel condensation/aza-Michael addition utilizing TiO2 nanoparticles. The Sonogashira coupling of 2-chloroquinolinyl moiety of the quinolinone, 3 gave unprecedented cyclised products 1,6-naphthyridines, 5 through cascade reaction in good yields and purity.
引用
收藏
页码：919 / 925
页数：7
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