Omega-3 fatty acids-loaded lipid nanoparticles for patient-convenient oral bioavailability enhancement

被引：18

作者：

Muchow, M. ^{[1
,2
]}

Schmitz, E. I. ^{[1
]}

Despatova, N. ^{[1
]}

Maincent, P. ^{[2
]}

Mueller, R. H. ^{[1
]}

机构：

[1] Free Univ Berlin, Dept Pharm, D-12169 Berlin, Germany

[2] Univ Henri Poincare, Lab Pharmaceut Technol & Biopharm, Nancy, France

来源：

PHARMAZIE | 2009年 / 64卷 / 08期

关键词：

COLON-CANCER; SURFACTANTS; DISEASE; HEALTH;

D O I：

10.1691/ph.2009.9084

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Omega-3 fatty acids are commonly used as food supplements not only for their positive effects on the blood lipid profile but also for their cardioprotective properties. The majority of the commercially available products is made out of fish oil. Apart from the unpleasant side effects, up to 10 capsules per day have to be taken by the patients. This article describes the development and characterisation of an alternative lipid nanoparticle delivery system, which has the potential to reduce side effects and enhance bioavailability.

引用

页码：499 / 504

页数：6

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