Features of the NIH atlas small animal PET scanner and its use with a coaxial small animal volume CT scanner

ATLAS (Advanced Technology Laboratory Animal Scanner), a small animal PET scanner designed to image animals the size of rats and mice, is about to enter service on the NIH campus in Bethesda, Maryland. This system is the first small animal PET scanner with a depth-of-interaction capability and the first to use iterative resolution recovery algorithms, rather than conventional filtered back projection, for "production" image reconstruction. ATLAS is also proximate to, and co-axial with, a high, resolution small animal CT scanner. When fully integrated, spatially registered PET and CT images of each animal will be used to correct the emission data for radiation attenuation and to aid in target identification. In this report we describe some of the technical and functional features of this system and illustrate how these features are used in an actual small animal imaging study.