Effects of L-arginine on various types of pain sensitivity

被引：4

作者：

Severyanova, L. A. ^{[1
]}

Bobyntsev, I. I. ^{[1
]}

Kir'yanova, N. A. ^{[1
]}

Dolgintsev, A. E. ^{[1
]}

机构：

[1] Kursk State Med Univ, Dept Pathophysiol, Kursk, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2006年 / 141卷 / 05期

关键词：

L-arginine; pain; electrocutaneous stimulation; thermal pain stimulation;

D O I：

10.1007/s10517-006-0222-0

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Intraperitoneal injection of L-arginine to male Wistar rats 12 min before the start of the experiment produced a nociceptive effect on models of electrocutancous stimulation of the tail or hot-plate test and increased nociceptive behavior due to high sensitivity of supraspinal nociceptive structures to this compound. The nociceptive effect of this amino acid was more pronounced and persistent under conditions of electrocutaneous stimulation.

引用

页码：567 / 570

页数：4

共 50 条

[31] The effects of L-arginine on crypt cell hyperproliferation in colorectal cancer [J].

Ma, QY ;

Williamson, KE ;

O'Rourke, D ;

Rowlands, BJ .

JOURNAL OF SURGICAL RESEARCH, 1999, 81 (02) :181-188

[32] Dexamethasone-induced hypertension in the rat: Effects of L-arginine [J].

Li, M ;

Fraser, T ;

Wang, J ;

Whitworth, JA .

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 1997, 24 (9-10) :730-732

[33] Effects of L-arginine on spontaneous contraction of the rat portal vein [J].

Shimamura, K ;

Zhou, M ;

Toba, M ;

Kimura, S ;

Higuchi, T ;

Kawaguchi, H ;

Sekiguchi, F ;

Sunano, S .

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 2003, 446 (01) :30-35

[34] EFFECTS OF L-ARGININE ON SYSTEMIC AND RENAL HEMODYNAMICS IN CONSCIOUS DOGS [J].

MURAKAMI, M ;

SUZUKI, H ;

ICHIHARA, A ;

NAITOH, M ;

NAKAMOTO, H ;

SARUTA, T .

CLINICAL SCIENCE, 1991, 81 (06) :727-732

[35] Comparative analysis of the neuronal activation and cardiovascular effects of nitroglycerin, sodium nitroprusside and L-arginine [J].

Tassorelli, C ;

Greco, R ;

Cappelletti, D ;

Sandrini, G ;

Nappi, G .

BRAIN RESEARCH, 2005, 1051 (1-2) :17-24

[36] Intracellular L-arginine concentration does not determine NO production in endothelial cells: Implications on the "L-arginine paradox" [J].

Shin, Soyoung ;

Mohan, Srinidi ;

Fung, Ho-Leung .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2011, 414 (04) :660-663

[37] Effects of Nω-nitro-L-arginine and L-arginine on quinolinic acid-induced lipid peroxidation [J].

Santamaría, A ;

Santamaria, D ;

Díaz-Muñoz, M ;

Espinoza-González, V ;

Ríos, C .

TOXICOLOGY LETTERS, 1997, 93 (2-3) :117-124

[38] Relation of L-arginine to airway hyperreactivity [J].

Strapkova, A. ;

Antosova, M. ;

Nosalova, G. .

GENERAL PHYSIOLOGY AND BIOPHYSICS, 2008, 27 (02) :85-91

[39] BENEFICIAL CIRCULATORY EFFECT OF L-ARGININE [J].

NAKAKI, T ;

KATO, R .

JAPANESE JOURNAL OF PHARMACOLOGY, 1994, 66 (02) :167-171

[40] Fluorometric enzymatic assay of L-arginine [J].

Stasyuk, Nataliya ;

Gayda, Galina ;

Yepremyan, Hismik ;

Stepien, Agnieszka ;

Gonchar, Mykhailo .

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2017, 170 :184-190

← 1 2 3 4 5 →