Effects of L-arginine on various types of pain sensitivity

被引:4
作者
Severyanova, L. A. [1 ]
Bobyntsev, I. I. [1 ]
Kir'yanova, N. A. [1 ]
Dolgintsev, A. E. [1 ]
机构
[1] Kursk State Med Univ, Dept Pathophysiol, Kursk, Russia
关键词
L-arginine; pain; electrocutaneous stimulation; thermal pain stimulation;
D O I
10.1007/s10517-006-0222-0
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Intraperitoneal injection of L-arginine to male Wistar rats 12 min before the start of the experiment produced a nociceptive effect on models of electrocutancous stimulation of the tail or hot-plate test and increased nociceptive behavior due to high sensitivity of supraspinal nociceptive structures to this compound. The nociceptive effect of this amino acid was more pronounced and persistent under conditions of electrocutaneous stimulation.
引用
收藏
页码:567 / 570
页数:4
相关论文
共 50 条
[21]   MELAS and L-arginine therapy [J].
Koga, Yasutoshi ;
Akita, Yukhiro ;
Nishioka, Junko ;
Yatsuga, Shuichi ;
Povalko, Nataliya ;
Katayama, Koujyu ;
Matsuishi, Toyojiro .
MITOCHONDRION, 2007, 7 (1-2) :133-139
[22]   L-Arginine in coronary atherosclerosis [J].
Tentolouris, C ;
Tousoulis, D ;
Goumas, G ;
Stefanadis, C ;
Davies, G ;
Toutouzas, P .
INTERNATIONAL JOURNAL OF CARDIOLOGY, 2000, 75 (2-3) :123-128
[23]   L-arginine:: Rediscovery in progress [J].
Tenebaum, A ;
Fisman, EZ ;
Motro, M .
CARDIOLOGY, 1998, 90 (03) :153-159
[24]   L-ARGININE AS AN ANTIHYPERTENSIVE AGENT [J].
HISHIKAWA, K ;
NAKAKI, T ;
SUZUKI, H ;
KATO, R ;
SARUTA, T .
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 1992, 20 :S196-S197
[25]   Iodides and polyiodides of L-arginine [J].
Petrosyan, A. M. ;
Giester, G. ;
Tonoyan, G. S. ;
Ghazaryan, V. V. ;
Zatikyan, A. L. ;
Chilingaryan, R. Yu. ;
Margaryan, A. A. ;
Mkrtchyan, A. H. .
JOURNAL OF MOLECULAR STRUCTURE, 2025, 1321
[26]   EFFECTS OF N-G-NITRO-L-ARGININE AND/OR L-ARGININE ON EXPERIMENTAL PULMONARY METASTASIS IN MICE [J].
YAMAMOTO, T ;
TERADA, N ;
NISHIZAWA, Y ;
TANAKA, H ;
AKEDO, H ;
SEIYAMA, A ;
SHIGA, T ;
KOSAKA, H .
CANCER LETTERS, 1994, 87 (01) :115-120
[27]   Effects of α-tocopherol, L-arginine, and quercetin on aggregation of human platelets [J].
Kobzar, G ;
Mardla, V ;
Samel, N .
NUTRITION RESEARCH, 2005, 25 (06) :569-575
[28]   PRESSOR, RENAL AND ENDOCRINE EFFECTS OF L-ARGININE IN ESSENTIAL HYPERTENSIVES [J].
PEDRINELLI, R ;
EBEL, M ;
CATAPANO, G ;
DELLOMO, G ;
DUCCI, M ;
DELCHICCA, M ;
CLERICO, A .
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1995, 48 (3-4) :195-201
[29]   L-ARGININE DOES NOT PREVENT THE RENAL EFFECTS OF ENDOTHELIN IN HUMANS [J].
BIJLSMA, JA ;
RABELINK, AJ ;
KAASJAGER, KAH ;
KOOMANS, HA .
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 1995, 5 (07) :1508-1516
[30]   Effects of L-arginine on physicochemical and sensory characteristics of pork sausage [J].
Zhou, Cunliu ;
Li, Jun ;
Tan, Shengjiang ;
Sun, Gaojun .
Advance Journal of Food Science and Technology, 2014, 6 (05) :660-667