Effects of L-arginine on various types of pain sensitivity

被引：4

作者：

Severyanova, L. A. ^{[1
]}

Bobyntsev, I. I. ^{[1
]}

Kir'yanova, N. A. ^{[1
]}

Dolgintsev, A. E. ^{[1
]}

机构：

[1] Kursk State Med Univ, Dept Pathophysiol, Kursk, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2006年 / 141卷 / 05期

关键词：

L-arginine; pain; electrocutaneous stimulation; thermal pain stimulation;

D O I：

10.1007/s10517-006-0222-0

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Intraperitoneal injection of L-arginine to male Wistar rats 12 min before the start of the experiment produced a nociceptive effect on models of electrocutancous stimulation of the tail or hot-plate test and increased nociceptive behavior due to high sensitivity of supraspinal nociceptive structures to this compound. The nociceptive effect of this amino acid was more pronounced and persistent under conditions of electrocutaneous stimulation.

引用

页码：567 / 570

页数：4

共 50 条

[1] Effects of L-arginine on various types of pain sensitivity [J].

L. A. Severyanova ;

I. I. Bobyntsev ;

N. A. Kir'yanova ;

M. E. Dolgintsev .

Bulletin of Experimental Biology and Medicine, 2006, 141 :567-570

[2] Effect of L-arginine in central spinal pain syndrome [J].

Danilova, EI ;

Grafova, VN ;

Kukushkin, ML ;

Zinkevich, VA .

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 1999, 127 (02) :144-147

[3] Vibrational spectra of L-arginine tetrafluoroborate and L-arginine perchlorate [J].

Petrosyan, A. M. .

VIBRATIONAL SPECTROSCOPY, 2006, 41 (01) :97-100

[4] Clinical and manometric effects of L-arginine in patients with chest pain and oesophageal motor disorders [J].

Bortolotti, M ;

Brunelli, F ;

Sarti, P ;

Miglioli, M .

ITALIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 1997, 29 (04) :320-324

[5] The effects on plasma L-arginine levels of combined oral L-citrulline and L-arginine supplementation in healthy males [J].

Suzuki, Takashi ;

Morita, Masahiko ;

Hayashi, Toshio ;

Kamimura, Ayako .

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2017, 81 (02) :372-375

[6] Anti-aging effects of L-arginine [J].

Gad, Mohamed Z. .

JOURNAL OF ADVANCED RESEARCH, 2010, 1 (03) :169-177

[7] Vascular effects of dietary L-arginine supplementation [J].

Preli, RB ;

Klein, KP ;

Herrington, DM .

ATHEROSCLEROSIS, 2002, 162 (01) :1-15

[8] L-Arginine: An amino acid with multiple effects [J].

Roth, E ;

Wessner, B .

WIENER KLINISCHE WOCHENSCHRIFT, 2005, 117 (19-20) :666-672

[9] Molecular pathology of MELAS and L-arginine effects [J].

Koga, Yasutoshi ;

Povalko, Nataliya ;

Nishioka, Junko ;

Katayama, Koujyu ;

Yatsuga, Shuichi ;

Matsuishi, Toyojiro .

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2012, 1820 (05) :608-614

[10] The L-arginine paradox:: Importance of the L-arginine/asymmetrical dimethylarginine ratio [J].

Bode-Boeger, Stefanie M. ;

Scalera, Fortunato ;

Ignarro, Louis J. .

PHARMACOLOGY & THERAPEUTICS, 2007, 114 (03) :295-306

← 1 2 3 4 5 →