Anti-fungal effects of phenolic amides isolated from the root bark of Lycium chinense

被引：111

作者：

Lee, DG

Park, Y

Kim, MR

Jung, HJ

Seu, YB

Hahm, KS

Woo, ER ^{[1
]}

机构：

[1] Chosun Univ, Res Ctr Prot Mat, Kwangju 501759, South Korea

[2] Chosun Univ, Coll Pharm, Kwangju 501759, South Korea

[3] Kyungpook Natl Univ, Dept Microbiol, Taegu 702701, South Korea

来源：

BIOTECHNOLOGY LETTERS | 2004年 / 26卷 / 14期

关键词：

anti-fungal activity; trans-N-caffeoyltyramine; dihydro-N-caffeoyltyramine; trans-N-feruloyloctopamine; Lycium chinense; Solanaceae;

D O I：

10.1023/B:BILE.0000035483.85790.f7

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Four phenolic amides, dihydro-N-caffeoyltyramine ( 1), trans-N-feruloyloctopamine ( 2), trans-N-caffeoyltyramine ( 3), and cis-N-caffeoyltyramine ( 4), were isolated from an ethyl acetate extract of the root bark of Lycium chinense Miller. All had an anti-fungal effect; compounds 1-3 were potent at 5-10 mug ml(-1) and were without hemolytic activity against human erythrocyte cells. Compound 4 was active at 40 mug ml(-1). All four compounds impeded the dimorphic transition of pathogen, Candida albicans.

引用

收藏

页码：1125 / 1130

页数：6

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共 39 条

[11] Difference in the effects of radioprotection between aerial and root parts of Lycium chinense [J].

Hsu, HY ;

Yang, JJ ;

Ho, YH ;

Lin, CC .

JOURNAL OF ETHNOPHARMACOLOGY, 1999, 64 (02) :101-108

[12] Targeted discovery of unusual diterpenoids with anti-fungal activity from the root of Euphorbia lathyris [J].

Wang, Yiwei ;

Xu, Shu ;

Zhang, Guodong ;

Li, Pirui ;

Liu, Chenyang ;

Zhou, Jiarui ;

Feng, Xu ;

Li, Linwei ;

Chen, Yu .

PHYTOCHEMISTRY, 2024, 225

[13] Assessing Anti-fungal Activity of Isolated Alveolar Macrophages by Confocal Microscopy [J].

Grimm, Melissa J. ;

D'Auria, Anthony C. ;

Segal, Brahm H. .

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 2014, (89)

[14] Three new diterpenoids isolated from Euphorbia nematocypha Hand.-Mazz and their anti-fungal activity [J].

Li, Rong-Shuai ;

Xu, Zhi-Chang ;

Qin, Ding-Mei ;

Huang, Jia-Bi ;

Wang, Meng-Ru ;

Zhao, Xue-Rong ;

Yang, Quan-Yu ;

Xiao, Wei-Lie ;

Wang, Rui-Rui ;

Li, Xiao-Li .

NATURAL PRODUCT RESEARCH, 2024, 38 (05) :838-847

[15] Isolation of anti-fungal phenolic compounds from petioles of two Hevea brasiliensis (rubber) genotypes and their effect on Phytophthora meadii [J].

Jayasuriya, KE ;

Whesunderaz, RLC ;

Deraniyagala, SA .

ANNALS OF APPLIED BIOLOGY, 2003, 142 (01) :63-69

[16] Evaluation on anti-fungal activity and synergy effects of essential oil and their constituents from Abies holophylla [J].

Kim S.-H. ;

Lee S.-Y. ;

Cho S.-M. ;

Hong C.-Y. ;

Park M.-J. ;

Choi I.-G. .

Journal of the Korean Wood Science and Technology, 2016, 44 (01) :113-123

[17] Two new anti-fungal diterpenoids from the husks of Oryza sativa [J].

Li, Gang ;

Xu, Qiao-Lin ;

He, Chun-Mei ;

Zeng, Lei ;

Wang, Hong-Feng .

PHYTOCHEMISTRY LETTERS, 2014, 10 :309-312

[18] Effects of hydration on termiticidal and anti-fungal activities of wood essential oils. [J].

Ohtani, Y ;

Kirishima, M ;

Sameshima, K .

MOKUZAI GAKKAISHI, 2001, 47 (03) :267-275

[19] ANTI-FUNGAL AND ANTI-TERMITE ACTIVITY OF EXTRACTIVES COMPOUNDS FROM THERMALLY MODIFIED ASH WOODS [J].

Condelier, Kevin ;

Thevenon, Marie-France ;

Collet, Robert ;

Gerardin, Philippe ;

Dumarcay, Stephan .

MADERAS-CIENCIA Y TECNOLOGIA, 2020, 22 (02) :223-240

[20] Composition and anti-fungal activity of the essential oil from Cameroonian Vitex rivularis Gurke [J].

Cabral, C. ;

Goncalves, M. J. ;

Cavaleiro, C. ;

Sales, F. ;

Boyom, F. ;

Salgueiro, L. .

NATURAL PRODUCT RESEARCH, 2009, 23 (16) :1478-1484

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