Properties of mixed monolayers of DPPC and viscoelasticity-giving substances

被引：2
|
作者：
Nanaumi, H
Tajima, M
Hosaka, M
Sakakibara, T
Takei, T
Takahashi, K
Ueno, M
机构：
[1] Sci Univ Tokyo, Fac Sci, Dept Appl Chem, Shinjuku Ku, Tokyo 1628601, Japan
[2] Nippon Fine Chem Co Ltd, Tokyo, Japan
[3] Tokyo Tanabe Seiyaku Co Ltd, Tokyo, Japan
[4] Sci Univ Tokyo, Inst Colloid & Surface Chem, Tokyo 162, Japan
来源：
COLLOIDS AND SURFACES B-BIOINTERFACES | 2000年 / 17卷 / 03期
关键词：
hysteresis loop; F-A curve; surface elastic modulus; surface viscosity; Maxwell model;
D O I：
10.1016/S0927-7765(99)00110-1
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
Static surface pressures and dynamic surface pressures for the mixed monolayers consisting of dipalmitoylphosphatidylcholine (DPPC), cholesterol linoleate (Cho-Linoleate), stearyl alcohol (StOH) and oleic acid (Ole-Ac) on the buffer were measured by using a modified Wilhelmy balance to obtain the surface rheological data such as surface elasticity, surface viscosity, and hysteresis loops of dynamic surface tension. These surface rheorogical data for the mixed monolayers with the molar ratios of DPPC:Cho-Linoleate:StOH:Ole-Ac = 11:1:7:1 showed similar to those obtained for a lung surfactant, TA, developed by Fujiwara et al. (T. Fujiwara et al., Elsevier Science, Amsterdam, 1984, pp. 479) which is known to be effective on the treatment of respiratory distress syndrome (RDS). (C) 2000 Elsevier Science B.V. All rights reserved.
引用
收藏
页码：167 / 174
页数：8
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