In vivo triple quantum filtered twisted projection sodium MRI of human articular cartilage

被引：55
作者：
Borthakur, A [1 ]
Hancu, I
Boada, FE
Shen, GX
Shapiro, EM
Reddy, R
机构：
[1] Univ Penn, Dept Radiol, Philadelphia, PA 19104 USA
[2] Univ Penn, Dept Chem, Philadelphia, PA 19104 USA
[3] Univ Pittsburgh, Med Ctr, Dept Phys, Pittsburgh, PA 15213 USA
[4] Univ Pittsburgh, Med Ctr, Dept Radiol, Pittsburgh, PA 15213 USA
来源：
JOURNAL OF MAGNETIC RESONANCE | 1999年 / 141卷 / 02期
关键词：
sodium; cartilage; multiple quantum filter; MRI;
D O I：
10.1006/jmre.1999.1923
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
In this work, we present the first triple quantum filtered (TQF) sodium MR images of the human knee joint in vivo. A 3D TQF data set of 16 slices was obtained in 20 min using a TQF pulse sequence preencoded to a twisted projection imaging readout. Images clearly demarcate patellar cartilage and also demonstrate fluid signal suppressed by the triple quantum filter. Biexponential transverse relaxation times were calculated by fitting the TQF free induction decay to a theoretical signal expression. The average values from three healthy volunteers were T*(2fall) = 9.59 +/- 0.35 ms and T*(rise) = 0.84 +/- 0.06 ms. Application of TQF imaging in biological tissues is discussed, (C) 1999 Academic Press.
引用
收藏
页码：286 / 290
页数：5
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