Copper(II) Sulfamate: An Efficient Catalyst for the One-Pot Synthesis of 3,4-Dihydropyrimidine-2(1H)-ones and thiones

被引：76
作者：
Liu, Chen-Jiang [1 ,2 ]
Wang, Ji-De [1 ,2 ]
机构：
[1] Xi An Jiao Tong Univ, Sch Sci, Xian 710049, Peoples R China
[2] Xinjiang Univ, Key Lab Oil & Gas Fine Chem, Minist Educ, Sch Chem & Chem Engn, Urumqi 830046, Peoples R China
来源：
MOLECULES | 2009年 / 14卷 / 02期
关键词：
Copper(II) sulfamate; Biginelli reaction; Dihydropyrimidinones; BIGINELLI REACTION; REUSABLE CATALYST; CONDENSATION; ACID; 3,4-DIHYDROPYRIMIDIN-2-(1H)-ONES/THIONES; 3,4-DIHYDROPYRIMIDIN-2(1H)-ONES; TRIFLATE; CHLORIDE; NITRATE;
D O I：
10.3390/molecules14020763
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A simple, efficient procedure for the one-pot Biginelli condensation reaction of aldehydes, beta-ketoesters and urea or thiourea employing copper(II) sulfamate as a novel catalyst is described. Compared to the classical Biginelli reaction conditions, the present method has the advantages of good yields, short reaction times and experimental simplicity.
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收藏
页码：763 / 770
页数：8
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