Extended-Spectrum-β-Lactamase-Producing Escherichia coli as Intestinal Colonizers in the German Community

被引：132

作者：

Valenza, Giuseppe ^{[1
]}

Nickel, Silke ^{[1
]}

Pfeifer, Yvonne ^{[2
]}

Eller, Christoph ^{[2
]}

Krupa, Elzbieta ^{[1
]}

Lehner-Reindl, Verena ^{[1
]}

Hoeller, Christiane ^{[3
]}

机构：

[1] Bavarian Hlth & Food Safety Author, Erlangen, Germany

[2] Robert Koch Inst, Nosocomial Pathogens & Antibiot Resistance FG13, Wernigerode, Germany

[3] Bavarian Hlth & Food Safety Author, Oberschleissheim, Germany

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2014年 / 58卷 / 02期

关键词：

FECAL CARRIAGE; KLEBSIELLA-PNEUMONIAE; RISK-FACTORS; PREVALENCE; ENTEROBACTERIACEAE; EMERGENCE; COLONIZATION; RESISTANCE; GENES; RATES;

D O I：

10.1128/AAC.01993-13

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We determined the presence of extended-spectrum-beta-lactamase (ESBL)-producing Escherichia coli among 3,344 study participants from the German community. Intestinal colonization was detected in 211 persons (6.3%), without significant differences among the different age groups. The majority (95.2%) of isolates harbored CTX-M-type ESBL, with CTX-M-15 (46%) and CTXM- 1 (24.2%) as the most common types. The finding of ESBL producers and one isolate additionally producing carbapenemase OXA-244 indicates a risk of dissemination of resistant bacteria outside the hospitals.

引用

页码：1228 / 1230

页数：3

共 23 条

[1] Prevalence and characterisation of extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli isolates in healthy volunteers in Tunisia [J].

Ben Sallem, R. ;

Ben Slama, K. ;

Estepa, V. ;

Jouini, A. ;

Gharsa, H. ;

Klibi, N. ;

Saenz, Y. ;

Ruiz-Larrea, F. ;

Boudabous, A. ;

Torres, C. .

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 2012, 31 (07) :1511-1516

[2] Prevalence and spread of extended-spectrum β-lactamase-producing Enterobacteriaceae in Europe [J].

Canton, R. ;

Novais, A. ;

Valverde, A. ;

Machado, E. ;

Peixe, L. ;

Baquero, F. ;

Coque, T. M. .

CLINICAL MICROBIOLOGY AND INFECTION, 2008, 14 :144-153

[3] Emergence of Carbapenem-Resistant Escherichia coli in Taiwan: Resistance Due to Combined CMY-2 Production and Porin Deficiency [J].

Chia, J. H. ;

Siu, L. K. ;

Su, L. H. ;

Lin, H. S. ;

Kuo, A. J. ;

Lee, M. H. ;

Wu, T. L. .

JOURNAL OF CHEMOTHERAPY, 2009, 21 (06) :621-626

[4] Rapid and simple determination of the Escherichia coli phylogenetic group [J].

Clermont, O ;

Bonacorsi, S ;

Bingen, E .

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2000, 66 (10) :4555-4558

[5]

Clinical and Laboratory Standards Institute, 2010, M100S19 CLIN LAB STA

[6] Presence of β-lactamases in extended-spectrum-cephalosporin-resistant Salmonella enterica of 30 different serovars in Germany 2005-11 [J].

Eller, Christoph ;

Simon, Sandra ;

Miller, Tatjana ;

Frick, Julia-Stefanie ;

Prager, Rita ;

Rabsch, Wolfgang ;

Guerra, Beatriz ;

Werner, Guido ;

Pfeifer, Yvonne .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2013, 68 (09) :1978-1981

[7] Molecular Identification of Extended-Spectrum-β-Lactamase Genes from Enterobacteriaceae Isolated from Healthy Human Carriers in Switzerland [J].

Geser, Nadine ;

Stephan, Roger ;

Korczak, Bozena M. ;

Beutin, Lothar ;

Haechler, Herbert .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2012, 56 (03) :1609-1612

[8] Emergence of carbapenem-non-susceptible extended-spectrum β-lactamase-producing Klebsiella pneumoniae isolates at the university hospital of Tubingen, Germany [J].

Groebner, Sabine ;

Linke, Dirk ;

Schuetz, Wolfgang ;

Fladerer, Claudia ;

Madlung, Johannes ;

Autenrieth, Ingo B. ;

Witte, Wolfgang ;

Pfeifer, Yvonne .

JOURNAL OF MEDICAL MICROBIOLOGY, 2009, 58 (07) :912-922

[9] High prevalence of CTX-M β-lactamases in faecal Escherichia coli strains from healthy humans in Fuzhou, China [J].

Li, Bin ;

Sun, Jing-Yong ;

Liu, Qing-Zhong ;

Han, Li-Zhong ;

Huang, Xin-Hong ;

Ni, Yu-Xing .

SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES, 2011, 43 (03) :170-174

[10] Prevalence of and risk factors associated with faecal carriage of CTX-M β-lactamase-producing Enterobacteriaceae in rural Thai communities [J].

Luvsansharav, Ulzii-Orshikh ;

Hirai, Itaru ;

Nakata, Arisa ;

Imura, Kaori ;

Yamauchi, Kou ;

Niki, Marie ;

Komalamisra, Chalit ;

Kusolsuk, Teera ;

Yamamoto, Yoshimasa .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2012, 67 (07) :1769-1774

← 1 2 3 →