Chitin Microneedles for an Easy-to-Use Tuberculosis Skin Test

被引：52

作者：

Jin, Jungho ^{[1
]}

Reese, Valerie ^{[2
]}

Coler, Rhea ^{[2
,3
]}

Carter, Darrick ^{[2
]}

Rolandi, Marco ^{[1
]}

机构：

[1] Univ Washington, Dept Mat Sci & Engn, Seattle, WA 98103 USA

[2] IDRI, Seattle, WA 98102 USA

[3] Univ Washington, Dept Global Hlth, Seattle, WA 98195 USA

来源：

ADVANCED HEALTHCARE MATERIALS | 2014年 / 3卷 / 03期

基金：

美国国家卫生研究院;

关键词：

microneedles; chitin; tuberculosis; diagnostics; Mantoux test; DISSOLVING MICRONEEDLES; POLYMER MICRONEEDLES; INTRADERMAL DELIVERY; GUINEA-PIGS; DRUG; FABRICATION; STABILITY; IMMUNIZATION; DIAGNOSIS; VACCINES;

D O I：

10.1002/adhm.201300185

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

An easy-to-use tuberculosis skin test is developed with chitin microneedles that deliver purified protein derivative at the correct skin depth and result in a positive test in BCG-immunized guinea pigs. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：349 / 353

页数：5

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