Vagus nerve stimulation in chronic treatment-resistant depression - Preliminary findings of an open-label study

被引：26
作者：
Corcoran, Ciaran D.
Thomas, Philip
Phillips, Jack
O'Keane, Veronica
机构：
[1] Royal Victoria Infirm, Mental Hlth Unit, Newcastle Upon Tyne NE1 4LP, Tyne & Wear, England
[2] Beaumont Hosp, Dublin 9, Ireland
[3] Kings Coll London, Inst Psychiat, London WC2R 2LS, England
来源：
BRITISH JOURNAL OF PSYCHIATRY | 2006年 / 189卷
关键词：
D O I：
10.1192/bjp.bp.105.018689
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
We evaluated the efficacy and safety of vagus nerve stimulation therapy in the treatment of 11 patients with chronic treatment-resistant depression. Mood was evaluated at frequent intervals over the year following implantation. All measures of depression, including the Hamilton Rating Scale for Depression reduced significantly. The response and remission rates were 55% and 27% respectively at 1 year. Side-effects were common, and some were severe.
引用
收藏
页码：282 / 283
页数：2
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