Immunomodulatory activity of the Ayurvedic formulation - "Ashwagandha churna

被引：10

作者：

Gupta, M. Suresh

Shivaprasad, H. N.

Kharya, M. D.

Rana, A. C.

机构：

[1] PES Coll Pharm, Dept Pharmacognosy, Bangalore 560050, Karnataka, India

[2] Dr HS Gour Vishwavidyalaya, Dept Pharmaceut Sci, Sagar, India

来源：

PHARMACEUTICAL BIOLOGY | 2006年 / 44卷 / 04期

关键词：

Ashwagandha churna; delayed-type hypersensitivity (DTH); neutrophil adhesion;

D O I：

10.1080/13880200600713949

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Immunomodulatory activity was evaluated for "ashwagandha churna", a reputed Ayurvedic herbal formulation. The experimental paradigms used were cellular (foot pad swelling) immune responses to the antigenic challenge by sheep RBCs (SRBCs) and the neutrophil adhesion test. On oral administration, ashwagandha churna showed a significant increase in neutrophil adhesion and delayed-type hypersensitivity (DTH) response. It is concluded that ashwagandha churna significantly potentiated the cellular immunity by facilitating the footpad thickness response to SRBCs in sensitized rats.

引用

页码：263 / 265

页数：3