Immunomodulatory activity of the Ayurvedic formulation - "Ashwagandha churna

被引:10
|
作者
Gupta, M. Suresh
Shivaprasad, H. N.
Kharya, M. D.
Rana, A. C.
机构
[1] PES Coll Pharm, Dept Pharmacognosy, Bangalore 560050, Karnataka, India
[2] Dr HS Gour Vishwavidyalaya, Dept Pharmaceut Sci, Sagar, India
关键词
Ashwagandha churna; delayed-type hypersensitivity (DTH); neutrophil adhesion;
D O I
10.1080/13880200600713949
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Immunomodulatory activity was evaluated for "ashwagandha churna", a reputed Ayurvedic herbal formulation. The experimental paradigms used were cellular (foot pad swelling) immune responses to the antigenic challenge by sheep RBCs (SRBCs) and the neutrophil adhesion test. On oral administration, ashwagandha churna showed a significant increase in neutrophil adhesion and delayed-type hypersensitivity (DTH) response. It is concluded that ashwagandha churna significantly potentiated the cellular immunity by facilitating the footpad thickness response to SRBCs in sensitized rats.
引用
收藏
页码:263 / 265
页数:3
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