Combined toxicity of fluoride and benzene hexachloride to rats

被引：0

作者：

Ramesh, N

Mohan, EM

Priya, CAYB

Stanley, VA

Pillai, KS

Murthy, PB

机构：

来源：

FLUORIDE | 1997年 / 30卷 / 02期

关键词：

benzene hexachloride (BHC); fluorosis; rat; synergism;

D O I：

暂无

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Sprague-Dawley rats were given various treatments of 10 ppm fluoride, 25 ppm fluoride, 25 ppm benzene hexachloride (BHC), 10 ppm fluoride + 25 ppm BHC, or 25 ppm fluoride + 25 ppm BHC for 16 weeks ad libitum. Rats showed a decrease in body weight gain, which could be attributable to BHC alone. A synergistic effect of fluoride and BHC was seen only in females given 25 ppm fluoride + 25 ppm BHC: a decrease in red blood cells (RBC) and relative weight of the ovary. Females were more susceptible to the toxicity of fluoride and BHC than males.

引用

页码：105 / 109

页数：5

共 22 条

[11] EFFECT OF SODIUM FLUORIDE ON RESPONSES TO VARIOUS CENTRAL NERVOUS SYSTEM AGENTS IN RATS [J].