Identification of a new HLA-DRB1 allele in three members of an Italian family

被引：2

作者：

Garino, E

Berrino, M

Mazzola, G

Boccadoro, M

Bruno, B

Bertinetto, F

Bertola, L

Caropreso, P

Frisaldi, E

Marin, F

Panniello, ML

Tondat, F

Dall'Omo, AM

机构：

[1] S Giovanni Battista Hosp, I-10126 Turin, Italy

[2] Univ Turin, San Giovanni Battista Hosp, Div Haematol, I-10124 Turin, Italy

[3] Univ Turin, Dept Genet Biol & Biochem, Turin, Italy

来源：

TISSUE ANTIGENS | 2004年 / 64卷 / 02期

关键词：

bone marrow transplantation; HLA-DRB1; new allele; sequence based typing;

D O I：

10.1111/j.1399-0039.2004.00262.x

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

A new human leucocyte antigen (IILA)-DRB1 allele, HLA-DRB1*1149, has been identified in three members of an Italian family during routine sequence based typing. This new allele differs from HLA- DRB1*110101 only for a single nucleotide substitution at position 113 of exon 2 resulting in an amino acid change from Valine (GTG) to Alanine (GCG) at codon 38.

引用

页码：210 / 212

页数：3

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