Limonoids from fruiting bodies of the wood-rot basidiomycete Fulvifomes xylocarpicola associated with the mangrove tree Xylocarpus granatum

被引：4

作者：

Isaka, Masahiko ^{[1
]}

Palasarn, Somporn ^{[1
]}

Sakayaroj, Jariya ^{[2
]}

Srichomthong, Kitlada ^{[1
]}

Nithithanasilp, Sutichai ^{[1
]}

Sappan, Malipan ^{[1
]}

机构：

[1] Natl Ctr Genet Engn & Biotechnol BIOTEC, 113 Thailand Sci Pk,Phaholyothin Rd, Klongluang 12120, Pathumthani, Thailand

[2] Walailak Univ, Sch Sci, 222 Thaiburi, Thasala 80161, Nakhon Si Thamm, Thailand

来源：

PHYTOCHEMISTRY | 2021年 / 181卷

关键词：

Fulvifomes xylocarpicola; Hymenochaetaceae; Xylocarpus granatum; Meliaceae; Limonoids; Antimalarial activity; KHAYA SENEGALENSIS; EXTRACTIVES;

D O I：

10.1016/j.phytochem.2020.112555

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Three previously undescribed limonoids, fulvifomins A-C, together with two known compounds, 6-deoxydetigloyl-swietenine acetate and methyl angolensate, were isolated from fruiting bodies of the wood-rot fungus Fulvifomes xylocarpicola (Hymenochaetaceae), growing on the mangrove tree Xylocarpus granatum (Meliaceae). The structures were elucidated on the basis of NMR spectroscopic and mass spectrometry data, and X-ray crystallographic analysis (for fulvifomin A). A number of similar limonoids have been isolated from higher plants of the family Meliaceae, including X. granatum. The present study represents a unique evidence that the associated basidiomycete also contains these limonoids. Fulvifomin B exhibited moderate antimalarial and antitubercular activites.

引用

页数：6

共 32 条

[1] EXTRACTIVES FROM KHAYA SENEGALENSIS A JUSS [J].