SINEs of cancer therapy success without ADAR1

被引：2
|
作者：
Zlotorynski, Eytan
机构：
[1] Nature Reviews Molecular Cell Biology,
来源：
NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2020年 / 21卷 / 12期
关键词：
D O I：
10.1038/s41580-020-00310-0
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
RNA editing by ADAR1 destabilizes epigenetic-treatment-induced retrotransposon stem-loops and thus dampens the immune response to the treatment, suggesting that ADAR1 could be a therapeutic target in combination with epigenetic therapy.
引用
收藏
页码：713 / 713
页数：1
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