SINEs of cancer therapy success without ADAR1

被引：2
|
作者：
Zlotorynski, Eytan
机构：
[1] Nature Reviews Molecular Cell Biology,
来源：
NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2020年 / 21卷 / 12期
关键词：
D O I：
10.1038/s41580-020-00310-0
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
RNA editing by ADAR1 destabilizes epigenetic-treatment-induced retrotransposon stem-loops and thus dampens the immune response to the treatment, suggesting that ADAR1 could be a therapeutic target in combination with epigenetic therapy.
引用
收藏
页码：713 / 713
页数：1
相关论文
共 50 条
  • [1] SINEs of cancer therapy success without ADAR1
    Eytan Zlotorynski
    Nature Reviews Molecular Cell Biology, 2020, 21 : 713 - 713
  • [2] Epigenetic therapy induces transcription of inverted SINEs and ADAR1 dependency
    Parinaz Mehdipour
    Sajid A. Marhon
    Ilias Ettayebi
    Ankur Chakravarthy
    Amir Hosseini
    Yadong Wang
    Fabíola Attié de Castro
    Helen Loo Yau
    Charles Ishak
    Sagi Abelson
    Catherine A. O’Brien
    Daniel D. De Carvalho
    Nature, 2020, 588 : 169 - 173
  • [3] Epigenetic therapy induces transcription of inverted SINEs and ADAR1 dependency
    Mehdipour, Parinaz
    Marhon, Sajid A.
    Ettayebi, Ilias
    Chakravarthy, Ankur
    Hosseini, Amir
    Wang, Yadong
    de Castro, Fabiola Attie
    Loo Yau, Helen
    Ishak, Charles
    Abelson, Sagi
    O'Brien, Catherine A.
    De Carvalho, Daniel D.
    NATURE, 2020, 588 (7836) : 169 - +
  • [4] Publisher Correction: Epigenetic therapy induces transcription of inverted SINEs and ADAR1 dependency
    Parinaz Mehdipour
    Sajid A. Marhon
    Ilias Ettayebi
    Ankur Chakravarthy
    Amir Hosseini
    Yadong Wang
    Fabíola Attié de Castro
    Helen Loo Yau
    Charles Ishak
    Sagi Abelson
    Catherine A. O’Brien
    Daniel D. De Carvalho
    Nature, 2021, 591 : E20 - E20
  • [5] Targeting ADAR1 for Mesothelioma Therapy
    Jacobson, B.
    Stoian, E.
    Khadlikar, R.
    Lan, K.
    Saveraid, H.
    Sehgal, A.
    Patel, M.
    Kratzke, R.
    JOURNAL OF THORACIC ONCOLOGY, 2024, 19 (10) : S685 - S685
  • [6] Epigenetic therapy induces transcription of inverted SINEs and ADAR1 dependency (vol 588, pg 169, 2020)
    Mehdipour, Parinaz
    Marhon, Sajid A.
    Ettayebi, Ilias
    Chakravarthy, Ankur
    Hosseini, Amir
    Wang, Yadong
    de Castro, Fabiola Attie
    Yau, Helen Loo
    Ishak, Charles
    Abelson, Sagi
    O'Brien, Catherine A.
    De Carvalho, Daniel D.
    NATURE, 2021, 591 (7850) : E20 - E20
  • [7] ADAR1 Editing and its Role in Cancer
    Xu, Li-Di
    Ohman, Marie
    GENES, 2019, 10 (01)
  • [8] ADAR1 and MicroRNA; A Hidden Crosstalk in Cancer
    Cho, Charles J.
    Myung, Seung-Jae
    Chang, Suhwan
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017, 18 (04):
  • [9] Dependency on the adenosine deaminase ADAR1 in cancer cells
    Nahimana, Aimable
    Cloux, Anne-Julie
    ElMokh, Oussama
    Duchosal, Michel A.
    SWISS MEDICAL WEEKLY, 2019, 149 : 18S - 18S
  • [10] Dependency on the adenosine deaminase ADAR1 in cancer cells
    Gannon, H.
    Zou, T.
    Kiessling, M.
    Meyerson, M.
    ONCOLOGY RESEARCH AND TREATMENT, 2020, 43 (SUPPL 4) : 196 - 197
12345