Recent advances in Staphylococcus aureus infection: focus on vaccine development

被引：56

作者：

Ansari, Shamshul ^{[1
]}

Jha, Rajesh Kumar ^{[2
]}

Mishra, Shyam Kumar ^{[3
]}

Tiwari, Birendra Raj ^{[4
]}

Asaad, Ahmed Morad ^{[5
]}

机构：

[1] Chitwan Med Coll & Teaching Hosp, Dept Microbiol, POB 42, Bharatpur, Chitwan, Nepal

[2] Saba Univ, Dept Syst & Dis Pharmacol, Sch Med, Saba, Netherlands

[3] Tribhuvan Univ, Dept Microbiol, Inst Med, Maharajgunj Med Campus, Kathmandu, Nepal

[4] St James Sch Med, Dept Microbiol, Pk Ridge, Anguilla

[5] Zagazig Univ, Dept Microbiol, Fac Med, Zagazig, Egypt

来源：

INFECTION AND DRUG RESISTANCE | 2019年 / 12卷

关键词：

active immunization; passive immunization; Staphylococcus aureus; vaccine; CONTROL CONSORTIUM REPORT; SILVER NANOPARTICLES; CAPSULAR POLYSACCHARIDE; ANTIBIOTIC-RESISTANCE; MONOCLONAL-ANTIBODIES; PROTEIN-A; ANTIMICROBIAL RESISTANCE; PASSIVE-IMMUNIZATION; DECREASES SEVERITY; ALPHA-HEMOLYSIN;

D O I：

10.2147/IDR.S175014

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Staphylococcus aureus normally colonizes the nasal cavity and pharynx. After breaching the normal habitat, the organism is able to cause a number of infections at any site of the body. The development of antibiotic resistance has created a global challenge for treating infections. Therefore, protection by vaccines may provide valuable measures. Currently, several vaccine candidates have been prepared which are either in preclinical phase or in early clinical phase, whereas several candidates have failed to show a protective efficacy in human subjects. Approaches have also been made in the development of monoclonal or polyclonal antibodies for passive immunization to protect from S. aureus infections. Therefore, in this review we have summarized the findings of recently published scientific literature to make a concise report.

引用

页码：1243 / 1255

页数：13

共 142 条

[1] S-aureus Infections in Chicago, 2006-2014: Increase in CA MSSA and Decrease in MRSA Incidence [J].

Acree, M. Ellen ;

Morgan, Ethan ;

David, Michael Z. .

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, 2017, 38 (10) :1226-1234

[2] Lower Antibody Levels to Staphylococcus aureus Exotoxins Are Associated With Sepsis in Hospitalized Adults With Invasive S. aureus Infections [J].

Adhikari, Rajan P. ;

Ajao, Adebola O. ;

Aman, M. Javad ;

Karauzum, Hatice ;

Sarwar, Jawad ;

Lydecker, Alison D. ;

Johnson, J. Kristie ;

Chinh Nguyen ;

Chen, Wilbur H. ;

Roghmann, Mary-Claire .

JOURNAL OF INFECTIOUS DISEASES, 2012, 206 (06) :915-923

[3] Biology and management of methicillin resistant Staphylococcus aureus in cystic fibrosis [J].

Akil, Nour ;

Muhlebach, Marianne S. .

PEDIATRIC PULMONOLOGY, 2018, 53 :S64-S74

[4] Retrospective analysis of antimicrobial resistance and bacterial spectrum of infection in Gabon, Central Africa [J].

Alabi, Abraham S. ;

Frielinghaus, Lisa ;

Kaba, Harry ;

Koesters, Katrin ;

Huson, Michaela A. M. ;

Kahl, Barbara C. ;

Peters, Georg ;

Grobusch, Martin P. ;

Issifou, Saadou ;

Kremsner, Peter G. ;

Schaumburg, Frieder .

BMC INFECTIOUS DISEASES, 2013, 13

[5] Mechanisms and consequences of bacterial resistance to antimicrobial peptides [J].

Andersson, D. I. ;

Hughes, D. ;

Kubicek-Sutherland, J. Z. .

DRUG RESISTANCE UPDATES, 2016, 26 :43-57

[6]

[Anonymous], ANN EP REP 2011 REP

[7]

[Anonymous], 2012, ACT BACT COR SURV RE

[8]

Ansari S, 2015, J Nepal Health Res Counc, V13, P126

[9] Threat of drug resistant Staphylococcus aureus to health in Nepal [J].

Ansari, Shamshul ;

Nepal, Hari Prasad ;

Gautam, Rajendra ;

Rayamajhi, Nabin ;

Shrestha, Sony ;

Upadhyay, Goma ;

Acharya, Anju ;

Chapagain, Moti Lal .

BMC INFECTIOUS DISEASES, 2014, 14

[10] High levels of Staphylococcus aureus and MRSA carriage in healthy population of Algiers revealed by additional enrichment and multisite screening [J].

Antri, Kenza ;

Akkou, Madjid ;

Bouchiat, Coralie ;

Bes, Michele ;

Martins-Simoes, Patricia ;

Dauwalder, Olivier ;

Tristan, Anne ;

Meugnier, Helene ;

Rasigade, Jean-Philippe ;

Etienne, Jerome ;

Vandenesch, Francois ;

Laurent, Frederic ;

Ramdani-Bouguessa, Nadjia .

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 2018, 37 (08) :1521-1529

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