Visible-Light-Driven Photocatalytic Initiation of Radical Thiol-Ene Reactions Using Bismuth Oxide

被引：81

作者：

Fadeyi, Olugbeminiyi O. ^{[1
]}

Mousseau, James J. ^{[1
]}

Feng, Yiqing ^{[1
]}

Allais, Christophe ^{[1
]}

Nuhant, Philippe ^{[1
]}

Chen, Ming Z. ^{[1
]}

Pierce, Betsy ^{[1
]}

Robinson, Ralph ^{[1
]}

机构：

[1] Pfizer Inc, Worldwide Med Chem, Groton, CT 06340 USA

来源：

ORGANIC LETTERS | 2015年 / 17卷 / 23期

关键词：

PHOTOREDOX CATALYSIS; CLICK CHEMISTRY; LARGAZOLE; INHIBITOR; THERAPY; BI2O3;

D O I：

10.1021/acs.orglett.5b03184

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A nontoxic and inexpensive photocatalytic initiation of anti-Markovnikov hydrothiolation of olefins using visible light is reported. This method is characterized by low catalyst loading, thereby enabling a mild and selective method for radical initiation in thiol-ene reactions between a wide scope of olefins and thiols.

引用

页码：5756 / 5759

页数：4

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