Clinical Factors Associated With the Diagnosis and Progression of Diabetic Nephropathy

被引：25

作者：

Liang, Shuang ^{[1
]}

Li, Qian ^{[2
]}

Zhu, Han-Yu ^{[1
]}

Zhou, Jian-Hui ^{[1
]}

Ding, Rui ^{[1
]}

Chen, Xiang-Mei ^{[1
]}

Cai, Guang-Yan ^{[1
]}

机构：

[1] Chinese Peoples Liberat Army Gen Hosp, Dept Nephrol, State Key Lab Kidney Dis, Beijing 100853, Peoples R China

[2] Chinese PLA 309 Hosp, Dept Pediat, Beijing 100091, Peoples R China

来源：

CELL BIOCHEMISTRY AND BIOPHYSICS | 2014年 / 70卷 / 01期

关键词：

Diabetic nephropathy; Non-diabetic renal disease; Renal function; Clinical factors; Disease progression; GLOMERULAR-FILTRATION-RATE; NONDIABETIC RENAL-DISEASE; CHRONIC KIDNEY-DISEASE; BLOOD-PRESSURE CONTROL; POST-HOC ANALYSIS; SERUM CYSTATIN-C; CARDIOVASCULAR EVENTS; GLYCEMIC CONTROL; ESTIMATED GFR; MELLITUS;

D O I：

10.1007/s12013-014-9892-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

As an important complication of diabetic mellitus, diabetic nephropathy (DN) has been the main cause of end-stage renal disease. It is of great importance to diagnose DN early, and to identify the risk factors of disease progression in order to carry out in-time and effective therapies. Previous literatures have reported the role of several clinical factors in the diagnosis and progression of DN, including age, longer diabetes duration, diabetic retinopathy, higher level of hypertension and HbA1c, and so on. However, the significance of these clinical factors is still controversial and limited. This review aimed to evaluate the values and limitations of these factors in diagnosing and predicting the renal outcome of DN.

引用

页码：9 / 15

页数：7

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