Relevance of Allergy in Adult Asthma

被引：11
作者：
Mathur, Sameer K. [1 ,2 ,3 ]
Viswanathan, Ravi K. [1 ]
机构：
[1] Univ Wisconsin, Sch Med, Madison, WI 53792 USA
[2] William S Middleton Vet Hosp, Madison, WI USA
[3] Univ Wisconsin, Sch Med & Publ Hlth, Div Allergy Immunol & Crit Care, Dept Med, Madison, WI 53792 USA
来源：
CURRENT ALLERGY AND ASTHMA REPORTS | 2014年 / 14卷 / 05期
基金：
美国国家卫生研究院;
关键词：
Asthma; Allergy; Adult asthma; Atopy; Phenotype; Asthma control; Airway inflammation; One airway hypothesis; IL-5; MESSENGER-RNA; BRONCHIAL HYPERREACTIVITY; ATOPY; CHILDHOOD; SEVERITY; CHILDREN; DISEASE; IDENTIFICATION; SENSITIZATION; EOSINOPHILIA;
D O I：
10.1007/s11882-014-0437-5
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
Recent studies on asthma have demonstrated multiple phenotypes, based on the clinical characteristics of the disease. With the current interest in personalized medicine, the question arises whether the presence of allergic sensitization has any relevance for these phenotypes and the management of asthma. This review will examine the current knowledge of asthma phenotypes and the impact of atopy on asthma diagnosis and severity in adults. In addition, this review will address whether therapies targeted at the atopic axis help improve asthma outcomes, including lung function indices and exacerbations.
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页数：5
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