A recyclable copper catalysis in quinoxaline synthesis from α-hydroxyketones and o-phenylenediamines

被引：33

作者：

Cho, Chan Sik ^{[1
]}

Ren, Wen Xiu ^{[1
]}

机构：

[1] Kyungpook Natl Univ, Dept Appl Chem, Taegu 702701, South Korea

来源：

JOURNAL OF ORGANOMETALLIC CHEMISTRY | 2009年 / 694卷 / 19期

关键词：

alpha-Hydroxyketones; Oxidative cyclization; o-Phenylenediamines; Quinoxalines; Recyclable copper catalyst; FRIEDLANDER QUINOLINE SYNTHESIS; TANDEM OXIDATION PROCESSES; PRIMARY ALCOHOLS; 2-AMINOBENZYL ALCOHOL; SECONDARY ALCOHOLS; AEROBIC OXIDATION; BETA-ALKYLATION; KETONES; CYCLIZATION; SOLVENT;

D O I：

10.1016/j.jorganchem.2009.06.002

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

o-Phenylenediamines react with alpha-hydroxyketones in toluene at 100 degrees C in the presence of a catalytic amount of a copper catalyst along with MS 4A under O(2) atmosphere to afford the corresponding quinoxalines in high yields. The catalytic system could be easily recovered and reused several times without any loss of catalytic activity. (C) 2009 Elsevier B.V. All rights reserved.

引用

页码：3215 / 3217

页数：3