(endo, endo)-9-benzyl-9-azabicyclo[3.3.1]nonane-2,6-diol:: An intermediate for the preparation of indole alkaloids of the macroline/sarpagine series

被引：0
作者：
Gennet, D
Michel, P
Rassat, A
机构：
[1] Ecole Normale Super, F-75231 Paris 05, France
[2] CNRS, F-75231 Paris 05, France
来源：
SYNTHESIS-STUTTGART | 2000年 / 03期
关键词：
bicyclic compounds; indoles; natural products; macroline/sarpagine alkaloids; Fischer indolization; heterocycles;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Two intermediates 9b and 9c already used by Cook and Magnus in their syntheses of indole alkaloids were obtained from the title compound 1 through a Fischer indolization procedure. Related tetracyclic intermediates 6 and 8 were also prepared: 6 having substituents at position 2 or 4 were directly obtained, while 8 with substituents at position 1 or 3 were selectively obtained through a convenient protection-deprotection scheme.
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页码：447 / 451
页数：5
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