Current options for the treatment of neoplastic meningitis

被引：10
作者：
Cokgor, I
Friedman, AH
Friedman, HS
机构：
[1] Duke Univ, Med Ctr, Dept Med, Durham, NC 27710 USA
[2] Duke Univ, Med Ctr, Dept Surg, Durham, NC 27710 USA
[3] Duke Univ, Med Ctr, Dept Pediat, Durham, NC 27710 USA
来源：
JOURNAL OF NEURO-ONCOLOGY | 2002年 / 60卷 / 01期
关键词：
neoplastic; meningitis; cancer treatment; chemotherapy; intrathecal;
D O I：
10.1023/A:1020200317464
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Neoplastic meningitis, which is the diffuse involvement of the leptomeninges by infiltrating cancer cells, may be caused by many systemic tumors. The treatment options for neoplastic meningitis disease remain unsatisfactory. In this review article, we discuss the pathogenesis and cytology of neoplastic meningitis and the options for treatment, including intrathecal chemotherapy, systemic chemotherapy, and newer agents such as cytokines and monoclonal antibodies.
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收藏
页码：79 / 88
页数：10
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