Quantitative phase imaging unit

被引:89
作者
Lee, KyeoReh [1 ]
Park, YongKeun [1 ]
机构
[1] Korea Adv Inst Sci & Technol, Dept Phys, Taejon 305701, South Korea
基金
新加坡国家研究基金会;
关键词
INTERFERENCE-CONTRAST MICROSCOPY; RED-BLOOD-CELLS; DIFFRACTION PHASE; LIGHT-SCATTERING; DIC MICROSCOPY; LIVING CELLS; DYNAMICS; COMPACT; OBJECTS; INTERFEROMETER;
D O I
10.1364/OL.39.003630
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
A simple and cost-effective method is presented for quantitative phase imaging. A common-path lateral phase shifting interferometer is realized through attaching a compact filter set to the output port of an existing microscope. The working principles, design criteria, and limitations are also derived and explained. In order to demonstrate the capability and applicability of the method, the optical phase images of a microsphere and individual human red blood cells are measured with high stability. (C) 2014 Optical Society of America
引用
收藏
页码:3630 / 3633
页数:4
相关论文
共 42 条
[1]   Compact, common path quantitative phase microscopic techniques for imaging cell dynamics [J].
Anand, A. ;
Vora, P. ;
Mahajan, S. ;
Trivedi, V. ;
Chhaniwal, V. ;
Singh, A. ;
Leitgeb, R. ;
Javidi, B. .
PRAMANA-JOURNAL OF PHYSICS, 2014, 82 (01) :71-78
[2]   Linear phase imaging using differential interference contrast microscopy [J].
Arnison, MR ;
Larkin, KG ;
Sheppard, CJR ;
Smith, NI ;
Cogswell, CJ .
JOURNAL OF MICROSCOPY-OXFORD, 2004, 214 (01) :7-12
[3]   Cell imaging beyond the diffraction limit using sparse deconvolution spatial light interference microscopy [J].
Babacan, S. Derin ;
Wang, Zhuo ;
Minh Do ;
Popescu, Gabriel .
BIOMEDICAL OPTICS EXPRESS, 2011, 2 (07) :1815-1827
[4]   Quantitative imaging of complex samples by spiral phase contrast microscopy [J].
Bernet, S ;
Jesacher, A ;
Fürhapter, S ;
Maurer, C ;
Ritsch-Marte, M .
OPTICS EXPRESS, 2006, 14 (09) :3792-3805
[5]   Optical detection and measurement of living cell morphometric features with single-shot quantitative phase microscopy [J].
Bon, Pierre ;
Savatier, Julien ;
Merlin, Marine ;
Wattellier, Benoit ;
Monneret, Serge .
JOURNAL OF BIOMEDICAL OPTICS, 2012, 17 (07)
[6]   Quadriwave lateral shearing interferometry for quantitative phase microscopy of living cells [J].
Bon, Pierre ;
Maucort, Guillaume ;
Wattellier, Benoit ;
Monneret, Serge .
OPTICS EXPRESS, 2009, 17 (15) :13080-13094
[7]   Quantitative phase-contrast imaging with compact digital holographic microscope employing Lloyd's mirror [J].
Chhaniwal, Vani ;
Singh, Amardeep S. G. ;
Leitgeb, Rainer A. ;
Javidi, Bahram ;
Anand, Arun .
OPTICS LETTERS, 2012, 37 (24) :5127-5129
[8]   CONFOCAL DIFFERENTIAL INTERFERENCE CONTRAST (DIC) MICROSCOPY - INCLUDING A THEORETICAL-ANALYSIS OF CONVENTIONAL AND CONFOCAL DIC IMAGING [J].
COGSWELL, CJ ;
SHEPPARD, CJR .
JOURNAL OF MICROSCOPY-OXFORD, 1992, 165 :81-101
[9]   Wavefront image sensor chip [J].
Cui, Xiquan ;
Ren, Jian ;
Tearney, Guillermo J. ;
Yang, Changhuei .
OPTICS EXPRESS, 2010, 18 (16) :16685-16701
[10]   Fourier Transform Light Scattering of Inhomogeneous and Dynamic Structures [J].
Ding, Huafeng ;
Wang, Zhuo ;
Nguyen, Freddy ;
Boppart, Stephen A. ;
Popescu, Gabriel .
PHYSICAL REVIEW LETTERS, 2008, 101 (23)