Contemporary device management of cardiogenic shock following acute myocardial infarction

被引:3
作者
Suleiman, Tariq [1 ]
Scott, Alexander [2 ]
Tong, David [3 ]
Khanna, Vikram [4 ]
Kunadian, Vijay [3 ,4 ]
机构
[1] Brighton & Sussex Univ Hosp NHS Fdn Trust, Royal Sussex Cty Hosp, Dept Resp Med, Brighton, E Sussex, England
[2] South Tees Hosp NHS Fdn Trust, James Cook Univ Hosp, Dept Anaesthesia & Intens Care Med, Middlesbrough, Cleveland, England
[3] Newcastle Univ, Inst Cellular Med, PG Diploma Clin Trials, Fac Med Sci, 4th Floor,William Leech Bldg, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
[4] Newcastle Upon Tyne Hosp NHS Fdn Trust, Freeman Hosp, Cardiothorac Ctr, Newcastle Upon Tyne, Tyne & Wear, England
关键词
Cardiogenic shock; Acute myocardial infarction; Intra-aortic balloon pump; Extracorporeal membrane oxygenation; Impella; TandemHeart; INTRAAORTIC BALLOON PUMP; VENTRICULAR ASSIST DEVICE; EXTRACORPOREAL MEMBRANE-OXYGENATION; PERCUTANEOUS CORONARY INTERVENTION; MECHANICAL CIRCULATORY SUPPORT; HEART-FAILURE; IMPELLA; 2.5; GENDER-DIFFERENCES; VENOARTERIAL ECMO; LIFE-SUPPORT;
D O I
10.1007/s10741-021-10088-8
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Despite advances in the overall management of acute myocardial infarction (AMI), cardiogenic shock in the setting of AMI (CS-AMI) continues to be associated with poor patient outcomes. There are multiple devices that can be used in CS-AMI to support the failing circulation, although their utility in improving outcomes as compared with conventional pharmacotherapy of vasopressors and inotropes remains to be established. This contemporary review provides an update on the evidence base for each of these techniques. In CS-AMI, acute thrombotic occlusion of a major epicardial artery leads to hypoxia and myocardial ischaemia in the territory subtended by that vessel. The resultant regional dysfunction in myocardial contractility can severely compromise stroke volume and result in acute circulatory failure, systemic hypoperfusion, lactic acidosis, multi-organ failure and ultimately death.
引用
收藏
页码:915 / 925
页数:11
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