Ex-vivo lung perfusion: the model for the organ reconditioning hub

被引:27
|
作者
Yeung, Jonathan C. [1 ]
Cypel, Marcelo [1 ]
Keshavjee, Shaf [1 ]
机构
[1] Univ Toronto, Toronto Gen Hosp, Div Thorac Surg, Toronto Lung Transplant Program, Toronto, ON, Canada
关键词
ex-vivo lung perfusion; lung preservation; lung transplantation; organ procurement center; TRANSPLANTATION; HEART; DONOR;
D O I
10.1097/MOT.0000000000000404
中图分类号
R3 [基础医学]; R4 [临床医学];
学科分类号
1001 ; 1002 ; 100602 ;
摘要
Purpose of review Lung evaluation and reconditioning by ex-vivo lung perfusion (EVLP) is becoming increasingly established. We review strategies for broader implementation of this technology to transplant centers worldwide. Recent findings The organ reconditioning hub model is a viable strategy for disseminating EVLP to small and large transplant centers given the well tolerated prolongation of preservation time afforded by EVLP. Regulatory and process issues remain hurdles to be overcome. Summary EVLP demonstrates promise to increase lung utilization. Organ reconditioning hubs appear to be an efficient method of delivering this promise to all transplant centers, not necessarily only the largest ones. Organ allocation processes will need to adapt to this new paradigm of organ preservation
引用
收藏
页码:287 / 289
页数:3
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