The neurochemical hypothesis of 'theory of mind'

被引：41
作者：
Abu-Akel, A [1 ]
机构：
[1] PLD Res Ctr, Arara, Israel
来源：
MEDICAL HYPOTHESES | 2003年 / 60卷 / 03期
关键词：
D O I：
10.1016/S0306-9877(02)00406-1
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
This paper aims to explore the neurochemical basis of the ability to represent one's own or other's mental states such as intentions, beliefs, wants and knowledge, an ability often referred to as 'theory of mind'. Based on neurochemical and psychopharmacological investigations in autism and schizophrenia, pathologies in which this ability is impaired, it is hypothesized that 'theory of mind' abilities are contingent on the integrity of the serotonergic and dopaminergic system. This hypothesis is discussed in light of the system's neurochemical properties and role in cognition. It is suggested that specific abnormalities to this system can account for differences in the profile of 'theory of mind' impairments that may exist among patients belonging to different pathologies. (C) 2002 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：382 / 386
页数：5
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