Generalized Edema and Telangiectasia: Unusual Presentation of Intravascular Large B-cell Lymphoma

被引：0

作者：

Kao, Chia-Mao ^{[1
]}

Chang, Ying-Jui ^{[1
]}

Hsiao, Cheng-Hsiang ^{[2
]}

Hsu, Yu-Ling ^{[1
]}

Wang, Ping-Huai ^{[3
]}

Tsai, Tsung-Hua ^{[1
]}

Su, Lin-Hui ^{[1
]}

机构：

[1] Far Eastern Mem Hosp, Dept Dermatol, Taipei, Taiwan

[2] Natl Taiwan Univ Hosp, Dept Pathol, Taipei, Taiwan

[3] Far Eastern Mem Hosp, Dept Pulm Med, Taipei, Taiwan

来源：

DERMATOLOGICA SINICA | 2009年 / 27卷 / 04期

关键词：

Intravascular large B-cell lymphoma; Angiotropic lymphoma; Telangiectasia; SKIN BIOPSY; MANAGEMENT; DIAGNOSIS;

D O I：

暂无

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Intravascular large B-cell lyrnphoma is characterized by clusters of large neoplastic B cells within small blood vessels, most commonly in the dermis and subcutis. There is no nodal or parenchymal involvement until late in the disease, and its endothelial tropism is responsible for the variable clinical features. We report the case of a 51 year-old man who presented with fever, altered mental status, generalized edema, and profound telangiectasia. The diagnosis was made by a skin biopsy from the right thigh. Histology revealed ectatic vessels in the superficial dermis and large atypical lymphoid cells filling the small blood vessels in the deep dermis. Immunohistochemical staining showed strongly positive results for CD45 and CD79a. This was a rare case of intravascular large B-cell lymphoma with generalized edema and telangiectasia as the only cutaneous manifestation. (Dermatol Sinica 27: 248-253, 2009)

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页码：248 / 253

页数：6

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